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In response to OP, toilet training is best begun around age 1 year. Some say earlier or later, but that's the standard. They can be trained to use regular toilets or a litter box, but they produce so much liquid waste, and their feces is so smelly and unsanitary that it is best flushed away. Make sure you train them to wipe properly. Some humans, and this varies with breeds as well as individuals, are very tidy and will clean themselves very thoroughly. Others are lazy and need frequent reinforcement.
As for cleaning, its recommended that you train them to wash themselves daily, if not twice daily. By about age 7 they should be able to do so by themselves, but if they haven't been trained at that point it can be a hassle to train them. Unless you shave their head fur, it needs to be shampooed and conditioned daily. Again, they can be trained to do this, but humans, being what they are, will sometimes skimp on hygiene. As for their body hair, this usually needs to be shaved off for sanitary reasons. There is also a kind of laser hair removal that is permanent, and, while expensive, will save you in the long run. It can also be done to the head to make them completely hairless, which is ideal for those with allergies, or anyone without the time to care for their human's fur. Nails are best kept short. Too long, and they can get caught on things, tear, become, stubbed, etc. Nails are very sensitive parts of the human anatomy, and it is said that, aside from genital pain, the worst pain they feel is related to things being inserted under the nails or having the nails removed. If desired, some vets will remove them under anathesia, and make sure they don't grow back. While this will eliminate the potential of your pet human hurting itself or others with its nails, as well as the need to trim its nails regularly, it is a painful operation, and removes one of the few natural means of defense a human has.