>>717597Sayonara Zetsubou Sensei
Series really has no point or plot other than to talk about stuff (a la Azumanga or Lucky Star) but from the perspective of people who certain disorders (Komori here is a Hikkikomori, a girl who's afraid to leave her home... which ends up changing location to the school. Another character is a perfectionist, wanting everything to be done equally and properly), plus all the characters are moe in some way.
Maria and Komori are my favorites personally.